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RPGF2 Polyclonal Antibody, 20ul Vector Construction NEURL4 exists as two alternatively

SKU: 61592605219

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RPGF2 Polyclonal Antibody, 20ul Vector Construction NEURL4 exists as two alternativelyMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

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Description

NEURL4 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 17p13

The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction

DRAK1 and DRAK2 are localized to the nucleus

tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity

RPGF2 Polyclonal Antibody, 20ul Vector Construction NEURL4 exists as two alternativelyMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP GDP regulated switches that cycle between inactive GDP and active GTP bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

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