IRS-1 Polyclonal Antibody, 50ul[BT-AP04642] Buffers & Solutions This gene has been found

This gene has been found to be rearranged| mutated| or amplified in a series of tumours including anaplastic large cell lymphomas| neuroblastoma| and non-small cell lung cancer

including the type 1 cystatins (stefins)

which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a)

The protein is involved in repressing and activating a diverse number of promoters

IRS-1 Polyclonal Antibody, 50ul[BT-AP04642] Buffers & Solutions This gene has been foundIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.