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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B member

SKU: 63680179133

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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B memberThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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Description

SERPINB7 (serpin family B member 7) encodes a member of a family of proteins which function as protease inhibitors

Variations in this protein's sequence have been implicated in Alzheimer's disease

this mRNA is expressed only in testis

The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B memberThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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