SLIK2 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in CDKN1C are implicated

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

Catalytic activity:ATP + H(2)O + Ca(2+)(Cis) = ADP + phosphate + Ca(2+)(Trans)

which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway

Several transcript variants encoding different isoforms have been found for BCKDK

SLIK2 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in CDKN1C are implicatedThis gene encodes an integral membrane protein that contains two N terminal leucine rich repeats domains and contains C terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.