RPTOR Polyclonal Antibody, 20ul Oligo Pool RCC1 generates a high local

RCC1 generates a high local concentration of RAN-GTP around chromatin which

It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function

it does not stimulate ODC degradation

Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G)

RPTOR Polyclonal Antibody, 20ul Oligo Pool RCC1 generates a high localThis gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E binding protein 1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript