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SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Proteolytic processing is required to

SKU: 65025019238

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SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Proteolytic processing is required toThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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Description

Proteolytic processing is required to generate a mature subunit

This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner

This receptor binds insulin-like growth factor with a high affinity

It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion

SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 20ul Recombinant Protein Proteolytic processing is required toThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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