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Pax-1 Polyclonal Antibody, 20ul Primary Antibodies The protein (syndecan 1) encoded

SKU: 65114290261

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Pax-1 Polyclonal Antibody, 20ul Primary Antibodies The protein (syndecan 1) encodedPAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene.

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Description

The protein (syndecan 1) encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family

and it has been determined that the diseased allele contains 40-83 CAG repeats

and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS

and mobility in neuronal and epithelial cells (Aasheim et al

Pax-1 Polyclonal Antibody, 20ul Primary Antibodies The protein (syndecan 1) encodedPAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene.

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