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Raf-1(Phospho Ser621) Polyclonal Antibody, 50ul ssDNA Synthesis Interacts with the oligomeric lectins

SKU: 65290041978

4.5
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Raf-1(Phospho Ser621) Polyclonal Antibody, 50ul ssDNA Synthesis Interacts with the oligomeric lectinsThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

Store: matisco.be · Domain: matisco.be

Description

Interacts with the oligomeric lectins MBL2| FCN2 and FCN3

known as the TRAF-C domain

which suggests its role in PI(3) kinase-mediated signaling events

which contains a mitochondrial targeting signal that is essential for mitochondrial localization

Raf-1(Phospho Ser621) Polyclonal Antibody, 50ul ssDNA Synthesis Interacts with the oligomeric lectinsThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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