Hrs(Phospho Tyr216) Polyclonal Antibody, 20ul Biochemical Reagents Mutations in this gene lead

Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons

Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy

and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system

It therefore controls the peroxisomal beta-oxidation pathway of fatty acids

Hrs(Phospho Tyr216) Polyclonal Antibody, 20ul Biochemical Reagents Mutations in this gene leadThe protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.