CD42d Polyclonal Antibody, 50ul Liquid Storage Consumables Dok-4 is thought to play

Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation

Chromosomal translocation of this gene with the RARA (retinoic acid receptor| alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia

Multiple alternatively spliced transcript variants that encode the same protein have been detected

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

CD42d Polyclonal Antibody, 50ul Liquid Storage Consumables Dok-4 is thought to playHuman platelet glycoprotein V (GP5) is a part of the Ib V IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM