Apaf-1-ALT Polyclonal Antibody, 100ul Erlenmeyer Flasks making it ideal for labs

making it ideal for labs looking to increase throughput and save time

57% of pancreatic and 45% of stomach cancers

Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells

The alpha2A subtype inhibited transmitter release at high stimulation frequencies

Apaf-1-ALT Polyclonal Antibody, 100ul Erlenmeyer Flasks making it ideal for labsAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent