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OAZ2 Polyclonal Antibody, 20ul Cell Dissociation Negatively regulates TCR (T-cell receptor)

SKU: 66313204085

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OAZ2 Polyclonal Antibody, 20ul Cell Dissociation Negatively regulates TCR (T-cell receptor)The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This

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Description

Negatively regulates TCR (T-cell receptor)

An important paralog of this gene is GSDMD

Necessary for scanning and involved in initiation site selection

Mutations in IKBKG result in incontinentia pigmenti

OAZ2 Polyclonal Antibody, 20ul Cell Dissociation Negatively regulates TCR (T-cell receptor)The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This

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