Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies Mutations in this gene are

Mutations in this gene are associated with Alzheimer disease risk

This kinase has been shown to directly phosphorylate and activate Ikappa B kinases| and thus plays a role in NF-kappa B signaling pathway

Tumor necrosis factor ligand superfamily member 13B encoded by TNFSF13B is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family

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Raf-1(Phospho Ser642) Polyclonal Antibody, 20ul Organelle Studies Mutations in this gene areThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.