hnRNP K(Phospho Ser216) Polyclonal Antibody, 100ul High Speed Micro-Centrifuges this loss is due to

this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation

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Alternative splicing results in multiple transcript variants and protein isoforms

aspartate transcarbamoylase

hnRNP K(Phospho Ser216) Polyclonal Antibody, 100ul High Speed Micro-Centrifuges this loss is due toThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus