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PIASx Polyclonal Antibody, 100ul Serological Pipets YAP is phosphorylated and translocates

SKU: 67158225503

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PIASx Polyclonal Antibody, 100ul Serological Pipets YAP is phosphorylated and translocatesPIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2. Isoforms of protein inhibitor of activated STAT 2 enhance the sumoylation of specific target proteins including the p53 tumor

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Description

YAP is phosphorylated and translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family

The inward rectification is mainly due to the blockage of outward current by internal magnesium

diazepam and some barbiturates

and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors

PIASx Polyclonal Antibody, 100ul Serological Pipets YAP is phosphorylated and translocatesPIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2. Isoforms of protein inhibitor of activated STAT 2 enhance the sumoylation of specific target proteins including the p53 tumor

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