Phospho-CD28 (Y218) Polyclonal Antibody, 20ul sgRNA Oligos Stat5 is constitutively active in

Stat5 is constitutively active in some leukemic cell types

Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor

EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha)

The protein localizes to the nucleus and is down-regulated in some cancer cell lines

Phospho-CD28 (Y218) Polyclonal Antibody, 20ul sgRNA Oligos Stat5 is constitutively active inThe protein encoded by CD28 (CD28 molecule) is essential for T cell proliferation and survival, cytokine production, and T helper type 2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for CD28.