SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in this gene have

Mutations in this gene have been associated with several diseases

a protein required for the induction of genes by growth and differentiation factors

Transcripts of this gene have been reported in specimens of human testis

OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS)

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Mutations in this gene haveThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding