Hox-B9 Polyclonal Antibody, 50ul ADME Mutations in CUBN may play

Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia

Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

flasks and beakers

Hox-B9 Polyclonal Antibody, 50ul ADME Mutations in CUBN may playHOXB9 is a member of the Abd B homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. Homeobox protein Hox B9 functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.