DGK-Theta Polyclonal Antibody, 100ul Molecular Biologyn Mutations in this gene are

Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin

and it can promote cell survival in prostate cancer

The enzyme is also active with zinc

ALPK subfamily

DGK-Theta Polyclonal Antibody, 100ul Molecular Biologyn Mutations in this gene areDiacylglycerol kinase theta encoded by DGKQ contains three cysteine rich domains, a proline rich region, and a pleckstrin homology domain with an overlapping Ras associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI cycle during cell signal transduction.