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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis The encoded protein is targeted

SKU: 71075694066

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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis The encoded protein is targetedCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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Description

The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis

RAB3 GTPase activating non-catalytic protein subunit 2 forms the Rab3 GTPase-activating complex with RAB3GAP1

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

and sporadic cases of congenital cataracts and ocular anterior segment anomalies

RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis The encoded protein is targetedCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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