LIMK-1 Polyclonal Antibody, 100ul[BT-AP05017] Peptide Modification LXRA (NR1H3

LXRA (NR1H3

PTM:Phosphorylation/dephosphorylation states of Ser-151 are required for regulating transduction of CREB activity

The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways

q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2| and a t(8

LIMK-1 Polyclonal Antibody, 100ul[BT-AP05017] Peptide Modification LXRA (NR1H3There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase