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p53R2 Polyclonal Antibody, 100ul Vessels This gene is located in

SKU: 71732105705

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p53R2 Polyclonal Antibody, 100ul Vessels This gene is located inRRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial

Store: matisco.be · Domain: matisco.be

Description

This gene is located in an intron of the FBXL13 gene on the opposite strand

thyroid-associated orbitopathy

FOXR1 encodes a member of the forkhead box (FOX) family of transcription factors

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

p53R2 Polyclonal Antibody, 100ul Vessels This gene is located inRRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial

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