p53(Phospho Ser376) Polyclonal Antibody, 50ul Buffers & Solutions Mutations in ACTA1 cause nemaline

Mutations in ACTA1 cause nemaline myopathy type 3

Mutations in this gene may be associated with Parkinson's disease

The product of this gene is a member of the BAR domain protein family

The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins

p53(Phospho Ser376) Polyclonal Antibody, 50ul Buffers & Solutions Mutations in ACTA1 cause nemalineThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.