Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody, 50ul Glassware Sets is a lysosomal cysteine proteinase

is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules

possibly due to a functional defect in motile cilia

and was first identified as being upregulated in psoriasis tissue

The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains

Tie2(Phospho-Ser1119) Rabbit Polyclonal Antibody, 50ul Glassware Sets is a lysosomal cysteine proteinaseThis gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with