Raf-1 Polyclonal Antibody, 100ul[BT-AP13531] Drug Development and Evaluation a nucleotide-binding site (NBS) domain

a nucleotide-binding site (NBS) domain

Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation

disease:Defects in COL2A1 are a cause of primary avascular necrosis of femoral head (ANFH)

The TRIM family is characterized by a signature motif composed of a RING finger| one or more B-box domains| and a coiled-coil region

Raf-1 Polyclonal Antibody, 100ul[BT-AP13531] Drug Development and Evaluation a nucleotide-binding site (NBS) domainThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.