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PGD Polyclonal Antibody, 50ul Vortex Mixer They form a heterodimer with

SKU: 75853430892

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PLN185.00 PLN225.00

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PGD Polyclonal Antibody, 50ul Vortex Mixer They form a heterodimer with6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2| respectively| which is essential for the maturation and function of the DUOX enzyme complexes

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B)

A number of genes are fusion partners have been characterized

The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride

PGD Polyclonal Antibody, 50ul Vortex Mixer They form a heterodimer with6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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