JAK2 Rabbit Polyclonal Antibody, 50ul ADME Because of their central role

Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs

targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression

and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element

JAK2 Rabbit Polyclonal Antibody, 50ul ADME Because of their central roleThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.