SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays 2005 [PubMed 16108726])

2005 [PubMed 16108726])

Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency

This protease cleaves type II collagen more efficiently than types I and III

an inhibitor of angiogenesis and a growth suppressor of glioblastomas

SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays 2005 [PubMed 16108726])SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular