JAK2 Monoclonal Antibody, 100ul Mechanical Pipette It is located in the

It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS

The protein encoded by this gene is T-cell receptor zeta

Multiple alternatively spliced transcript variants have been identified in this gene

Mutations in this gene have been associated with medulloblastomas

JAK2 Monoclonal Antibody, 100ul Mechanical Pipette It is located in theThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.