HSF2B Rabbit Polyclonal Antibody, 100ul Gloves it does bind tightly to

it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

This gene encodes a member of the chaperonin family

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

HSF2B Rabbit Polyclonal Antibody, 100ul Gloves it does bind tightly toHSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation.