Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The protein encoded by this

The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription

and transcription factor erythroblastosis virus E26 oncogene homolog 1

The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor

PTM:Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The protein encoded by thisMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.