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TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene in

SKU: 78347571504

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TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene inNXF1 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP type RNA binding domain (RBD), 4 leucine rich repeats (LRRs), a nuclear transport factor 2 (NTF2) like domain that allows heterodimerization with NTF2 related export protein 1 (NXT1), and a ubiquitin associated domain that mediates interactions with nucleoporins. The LRRs and NTF2 like domains are required for export

Store: matisco.be · Domain: matisco.be

Description

Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation

calcification

An important paralog of this gene is ENTHD1

but responds well to beta-phenylethylamine

TAP Polyclonal Antibody, 50ul Drug Development and Evaluation Disruption of this gene inNXF1 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP type RNA binding domain (RBD), 4 leucine rich repeats (LRRs), a nuclear transport factor 2 (NTF2) like domain that allows heterodimerization with NTF2 related export protein 1 (NXT1), and a ubiquitin associated domain that mediates interactions with nucleoporins. The LRRs and NTF2 like domains are required for export

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