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Nephrocystin-5 Polyclonal Antibody, 50ul PCR Series Mitogen-activated protein kinase kinase kinase

SKU: 78728641287

4.7
PLN185.00 PLN234.00

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Nephrocystin-5 Polyclonal Antibody, 50ul PCR Series Mitogen-activated protein kinase kinase kinaseIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin binding motif containing protein 1 has a central coiled coil region and two calmodulin binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin binding motif containing protein 1 is thought to play a role in ciliary function. Defects

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Description

Mitogen-activated protein kinase kinase kinase kinase 3 activates key effectors in cell signalling

This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

Mutations in this gene cause cerebellar ataxia in humans

It also plays an important role in trafficking of T cells in thymus

Nephrocystin-5 Polyclonal Antibody, 50ul PCR Series Mitogen-activated protein kinase kinase kinaseIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin binding motif containing protein 1 has a central coiled coil region and two calmodulin binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin binding motif containing protein 1 is thought to play a role in ciliary function. Defects

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