CD137 Polyclonal Antibody, 100ul[BT-AP07268] Site-directed Mutagenesis Binds PLXNA1 (By similarity)

Binds PLXNA1 (By similarity)

Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1)

Also acts as a positive regulator of the Wnt signaling pathway

An important paralog of this gene is KIF23

CD137 Polyclonal Antibody, 100ul[BT-AP07268] Site-directed Mutagenesis Binds PLXNA1 (By similarity)The protein encoded by this gene is a member of the TNF receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR CD3 triggered activation, and regulate CD28 co stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been