ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator Alternative splicing of this PEG3

Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms

Mutations in this gene have be associated glycogen storage disease

Glycosyltransferases| such as SLC35B4| transport nucleotide sugars from the cytoplasm where they are synthesized| to the Golgi apparatus where they are utilized in the synthesis of glycoproteins| glycolipids| and proteoglycans (Ashikov et al

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator Alternative splicing of this PEG3ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation