DHX58 Polyclonal Antibody, 20ul Centrifugal Filter DAB1 is similar to disabled-1

DAB1 is similar to disabled-1

Mutations in this gene are associated with Cenani-Lenz syndrome

This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine

May play a role in the defense system against microorganisms

DHX58 Polyclonal Antibody, 20ul Centrifugal Filter DAB1 is similar to disabled-1Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,