AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing There are two alternate translation

There are two alternate translation start codons with this gene| which result in two forms of the protein

The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5

Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing There are two alternate translationThe protein encoded by this gene belongs to the family of P type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate