Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos suitable for use with most

suitable for use with most types of equipment

an aspartic endopeptidase

Alternative splicing results in multiple transcript variants encoding distinct isoforms

the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes

Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos suitable for use with mostCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals