Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Dok-5 and Dok-6 are more

Dok-5 and Dok-6 are more similar to each other than to the other Dok family members

The encoded protein is widely used as a marker for hematopoietic stem cells

Binding of the ligand inhibits cAMP accumulation

tissue specificity:Testis-specific

Mcl-1 Polyclonal Antibody, 50ul[BT-AP05274] Subcellular Fractions Dok-5 and Dok-6 are moreMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.