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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This family member is most

SKU: 82381542017

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FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This family member is mostFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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Description

This family member is most abundant in muscle but is expressed in all tissues

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This gene encodes a large protein that forms a structural component of the nuclear matrix

formed between homologous chromosomes during meiotic prophase

FKRP Polyclonal Antibody, 50ul Cell Culture & Maintenance This family member is mostFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.

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