RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The encoded protein also stabilizes

The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure

The protein has been implicated in the development of Alzheimer disease

Functional analysis showed that this gene product has both ATPase and DNA helicase activities

It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins

RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The encoded protein also stabilizesRFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have