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ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit these

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ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit theseThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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Description

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

IRX3 is a member of the Iroquois homeobox gene family (see IRX1

a MAM domain and a C-terminal GPI-anchoring site

Members of this family form the core of a highly conserved tumor suppressor network

ANGP2 Polyclonal Antibody, 50ul Organelle Studies The epitopes that elicit theseThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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