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p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles UCP2 (uncoupling protein 2)is expressed

SKU: 84529904757

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p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles UCP2 (uncoupling protein 2)is expressedThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

UCP2 (uncoupling protein 2)is expressed in many tissues

rather than maintenance methylation

Neural retina leucine zipper is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function

It has been shown to mediate the immunosuppressive signal of interleukin 10

p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles UCP2 (uncoupling protein 2)is expressedThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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