Rb(Phospho Ser780) Polyclonal Antibody, 20ul Dialysis Allelic variants of this gene

Allelic variants of this gene exist that confer susceptibility to diabetes mellitus

The SH2-binding sites putatively bind CRK| NCK and ABL SH2 domains

DHRS11 (Dehydrogenase/Reductase (SDR Family) Member 11) is a Protein Coding gene

The V0 domain consists of five different subunits: a

Rb(Phospho Ser780) Polyclonal Antibody, 20ul Dialysis Allelic variants of this geneThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.