CD152 Polyclonal Antibody, 50ul Drug Development and Evaluation IFITM2 (Interferon Induced Transmembrane Protein

IFITM2 (Interferon Induced Transmembrane Protein 2) is a Protein Coding gene

A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5

This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease

which interacts with histone deacetylase

CD152 Polyclonal Antibody, 50ul Drug Development and Evaluation IFITM2 (Interferon Induced Transmembrane ProteinThis gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in