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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in various

SKU: 8629849577

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SEK162.00 SEK203.00

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

RARs are involved in various biological processes

prostaglandin E2 secretion

with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane

They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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