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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Based on studies in chicken

SKU: 87252243449

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Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Based on studies in chickenThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

Store: matisco.be · Domain: matisco.be

Description

Based on studies in chicken and mouse

secondary structure can deter the protective function of this protein

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

Component of the little elongation complex (LEC)

Rad17 Polyclonal Antibody, 50ul[BT-AP07600] Immune Repertoire Sequencing Based on studies in chickenThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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