MIA Polyclonal Antibody, 100ul[BT-AP05403] Gel & Buffers Essential pre-mRNA splicing factor required

Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II

This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain

In nucleus

The encoded preproprotein is proteolytically processed to generate the mature protein

MIA Polyclonal Antibody, 100ul[BT-AP05403] Gel & Buffers Essential pre-mRNA splicing factor requiredThe product of CHD4 belongs to the SNF2 RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different