Rb Polyclonal Antibody, 50ul[BT-AP07693] Cell Transfection rheumatoid arthritis

rheumatoid arthritis

Five alternatively spliced transcript variants encoding distinct isoforms have been reported

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation

It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins

Rb Polyclonal Antibody, 50ul[BT-AP07693] Cell Transfection rheumatoid arthritisThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.