Rat Coagulation Factor 12, F12 ELISA Kit, 96T Metabolic enzymes tool compounds It is thought that FABPs

It is thought that FABPs roles include fatty acid uptake

Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1

Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2 (By similarity)

Several related pseudogenes have also been identified

Rat Coagulation Factor 12, F12 ELISA Kit, 96T Metabolic enzymes tool compounds It is thought that FABPsFactor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha factor XIIa and then trypsin cleaves it to beta factor XIIa. Alpha factor XIIa activates factor XI to factor XIa (By similarity).